Ultimately, translational research in glycation pathways involved in HCC may offer novel biomarkers to detect early HCC or monitor disease progression. A consideration of multiple AGE receptors as well as AGE effects on gut microbiota inflammatory pathways is also important. Future directions lie in elucidating mechanism with disease specific in vivo animal models and complementary in vitro studies. In elucidating mechanisms in HCC pathogenesis, the underlying aetiologies are important with viral hepatitis, alcoholic and non-alcoholic liver disease being the most common causes.
Consultez le profil complet sur LinkedIn et découvrez les relations de Daryl, ainsi que des emplois dans des entreprises similaires. This article will summarise the association between AGEs in liver disease and HCC progression. Voir le profil de Daryl Ah-Leung sur LinkedIn, le plus grand réseau professionnel mondial. They are abundant in Western diets and found endogenously at an increased rate in diabetes.
Sze Leung Ho is a Back-End Software Engineer at Manulife Global based in Toronto, Ontario. Her thesis project examines parental cultural socialization by. Advanced glycation end-products (AGEs) are a group of biologically active compounds that are formed when sugar moieties react non-enzymatically with amino groups. Back-End Software Engineer at Manulife Global. Vivian Leung is a PhD Candidate & Research Coordinator at FIFSW, University of Toronto. There is, therefore, an urgent need to explore novel areas which may be contributing to pathogenesis such as advanced glycation pathways, to better understand HCC progression. Hepatocellular carcinoma (HCC) is the second most common cause of cancer mortality worldwide and is the most rapidly growing indication for liver transplantation globally.